thp1 cells atcc Search Results


cat 300356 p804 thp 1  (CLS Cell Lines Service GmbH)
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CLS Cell Lines Service GmbH cat 300356 p804 thp 1
Cat 300356 P804 Thp 1, supplied by CLS Cell Lines Service GmbH, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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monocytic cells  (ATCC)
99
ATCC monocytic cells
Monocytic Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/thp1+cells+atcc/THP-1/pmc02374122-121-2-4
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monocytic cells - by Bioz Stars, 2026-10
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thp-1 cells  (BioResource International Inc)
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BioResource International Inc thp-1 cells
Thp 1 Cells, supplied by BioResource International Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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hct116 cells  (ATCC)
99
ATCC hct116 cells
A) Structure of the L3MBTL3 antagonist, UNC1215. B) Structure of biotin-UNC1215. C) UNC1215 does not disrupt the L3MBTL3-Cul4DCAF5 interaction. HEK293T (293T) cells were transiently transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 20 μM UNC1215 followed by biotin probe (200 nM) pulldown (n = 2). D) L3MBTL3 interacts with DCAF5 and DDB1 in HEK293T cells and E) <t>HCT116</t> cells. HEK293T or HCT116 cells were co-transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 5 μM UNC1215 followed by immunoprecipitation of L3MBTL3-HA (n = 2).
Hct116 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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hct116 cells - by Bioz Stars, 2026-10
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human cells  (ATCC)
99
ATCC human cells
A) Structure of the L3MBTL3 antagonist, UNC1215. B) Structure of biotin-UNC1215. C) UNC1215 does not disrupt the L3MBTL3-Cul4DCAF5 interaction. HEK293T (293T) cells were transiently transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 20 μM UNC1215 followed by biotin probe (200 nM) pulldown (n = 2). D) L3MBTL3 interacts with DCAF5 and DDB1 in HEK293T cells and E) <t>HCT116</t> cells. HEK293T or HCT116 cells were co-transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 5 μM UNC1215 followed by immunoprecipitation of L3MBTL3-HA (n = 2).
Human Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/thp1+cells+atcc/A549/pmc08540636-124-0-32
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human cells - by Bioz Stars, 2026-10
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human monocytic leukemia thp 1 cells  (ATCC)
94
ATCC human monocytic leukemia thp 1 cells
A) Structure of the L3MBTL3 antagonist, UNC1215. B) Structure of biotin-UNC1215. C) UNC1215 does not disrupt the L3MBTL3-Cul4DCAF5 interaction. HEK293T (293T) cells were transiently transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 20 μM UNC1215 followed by biotin probe (200 nM) pulldown (n = 2). D) L3MBTL3 interacts with DCAF5 and DDB1 in HEK293T cells and E) <t>HCT116</t> cells. HEK293T or HCT116 cells were co-transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 5 μM UNC1215 followed by immunoprecipitation of L3MBTL3-HA (n = 2).
Human Monocytic Leukemia Thp 1 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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human monocytic leukemia thp 1 cells - by Bioz Stars, 2026-10
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cell cultures  (ATCC)
99
ATCC cell cultures
A) Structure of the L3MBTL3 antagonist, UNC1215. B) Structure of biotin-UNC1215. C) UNC1215 does not disrupt the L3MBTL3-Cul4DCAF5 interaction. HEK293T (293T) cells were transiently transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 20 μM UNC1215 followed by biotin probe (200 nM) pulldown (n = 2). D) L3MBTL3 interacts with DCAF5 and DDB1 in HEK293T cells and E) <t>HCT116</t> cells. HEK293T or HCT116 cells were co-transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 5 μM UNC1215 followed by immunoprecipitation of L3MBTL3-HA (n = 2).
Cell Cultures, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/thp1+cells+atcc/22Rv1/pm41187563-468-25-38
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cell cultures - by Bioz Stars, 2026-10
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monocyte cells  (ATCC)
99
ATCC monocyte cells
A) Structure of the L3MBTL3 antagonist, UNC1215. B) Structure of biotin-UNC1215. C) UNC1215 does not disrupt the L3MBTL3-Cul4DCAF5 interaction. HEK293T (293T) cells were transiently transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 20 μM UNC1215 followed by biotin probe (200 nM) pulldown (n = 2). D) L3MBTL3 interacts with DCAF5 and DDB1 in HEK293T cells and E) <t>HCT116</t> cells. HEK293T or HCT116 cells were co-transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 5 μM UNC1215 followed by immunoprecipitation of L3MBTL3-HA (n = 2).
Monocyte Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/thp1+cells+atcc/BEAS-2B/pmc11804812-35-9-19
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monocyte cells - by Bioz Stars, 2026-10
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thp 1 tib202  (ATCC)
96
ATCC thp 1 tib202
A) Structure of the L3MBTL3 antagonist, UNC1215. B) Structure of biotin-UNC1215. C) UNC1215 does not disrupt the L3MBTL3-Cul4DCAF5 interaction. HEK293T (293T) cells were transiently transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 20 μM UNC1215 followed by biotin probe (200 nM) pulldown (n = 2). D) L3MBTL3 interacts with DCAF5 and DDB1 in HEK293T cells and E) <t>HCT116</t> cells. HEK293T or HCT116 cells were co-transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 5 μM UNC1215 followed by immunoprecipitation of L3MBTL3-HA (n = 2).
Thp 1 Tib202, supplied by ATCC, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/thp1+cells+atcc/RS4%3B11/pm39086976-174-34-33
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human aml cell lines  (ATCC)
99
ATCC human aml cell lines
A) Structure of the L3MBTL3 antagonist, UNC1215. B) Structure of biotin-UNC1215. C) UNC1215 does not disrupt the L3MBTL3-Cul4DCAF5 interaction. HEK293T (293T) cells were transiently transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 20 μM UNC1215 followed by biotin probe (200 nM) pulldown (n = 2). D) L3MBTL3 interacts with DCAF5 and DDB1 in HEK293T cells and E) <t>HCT116</t> cells. HEK293T or HCT116 cells were co-transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 5 μM UNC1215 followed by immunoprecipitation of L3MBTL3-HA (n = 2).
Human Aml Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/thp1+cells+atcc/HL-60/10__1158_slash_2159___8290__cd___17___0399-268-25-37
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human aml cell lines - by Bioz Stars, 2026-10
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aml cell lines thp 1  (DSMZ)
96
DSMZ aml cell lines thp 1
Figure 1: )e inhibitory effect of HHTon nine <t>AML</t> <t>cell</t> lines. (a) )e IC50 values of HHTon nine AML cell lines. (b) )e inhibitory effect of HHT on FLT3-ITD mutant cell lines was significantly higher than that in nonmutant ones. ∗P < 0.05.
Aml Cell Lines Thp 1, supplied by DSMZ, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/thp1+cells+atcc/THP-1/pm36081671-35-0-39
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ccr1 expressing cells a thp 1 cells thp 1 cells  (ATCC)
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ATCC ccr1 expressing cells a thp 1 cells thp 1 cells
Figure 1: )e inhibitory effect of HHTon nine <t>AML</t> <t>cell</t> lines. (a) )e IC50 values of HHTon nine AML cell lines. (b) )e inhibitory effect of HHT on FLT3-ITD mutant cell lines was significantly higher than that in nonmutant ones. ∗P < 0.05.
Ccr1 Expressing Cells A Thp 1 Cells Thp 1 Cells, supplied by ATCC, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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ccr1 expressing cells a thp 1 cells thp 1 cells - by Bioz Stars, 2026-10
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Image Search Results


A) Structure of the L3MBTL3 antagonist, UNC1215. B) Structure of biotin-UNC1215. C) UNC1215 does not disrupt the L3MBTL3-Cul4DCAF5 interaction. HEK293T (293T) cells were transiently transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 20 μM UNC1215 followed by biotin probe (200 nM) pulldown (n = 2). D) L3MBTL3 interacts with DCAF5 and DDB1 in HEK293T cells and E) HCT116 cells. HEK293T or HCT116 cells were co-transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 5 μM UNC1215 followed by immunoprecipitation of L3MBTL3-HA (n = 2).

Journal: Journal of the American Chemical Society

Article Title: Hijacking Methyl Reader Proteins for Nuclear-Specific Protein Degradation

doi: 10.1021/jacs.2c00874

Figure Lengend Snippet: A) Structure of the L3MBTL3 antagonist, UNC1215. B) Structure of biotin-UNC1215. C) UNC1215 does not disrupt the L3MBTL3-Cul4DCAF5 interaction. HEK293T (293T) cells were transiently transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 20 μM UNC1215 followed by biotin probe (200 nM) pulldown (n = 2). D) L3MBTL3 interacts with DCAF5 and DDB1 in HEK293T cells and E) HCT116 cells. HEK293T or HCT116 cells were co-transfected with L3MBTL3-HA and myc-DCAF5, lysed after 48 h and incubated in the presence or absence of 5 μM UNC1215 followed by immunoprecipitation of L3MBTL3-HA (n = 2).

Article Snippet: Cell lines HEK293T cells, THP1 and HCT116 cells were purchased from ATCC.

Techniques: Transfection, Incubation, Immunoprecipitation

A) Schematic of BRD and L3MBTL3 proteins in complex with the JQ1-UNC1215 PROTAC. Figure was created with BioRender.com Structure of KL-7. B) KL-7 degrades BRD2 in a dose-dependent manner in HCT116 cells. HCT116 cells were treated with increasing concentrations of KL-7 for 12 h. Quantitation is on the right and the quantified data represent mean ± SEM (n = 3, ****P<0.0001). C) BRD2 forms a ternary complex with L3MBTL3 in a KL-7 dependent manner. HEK293T cells were co-transfected with L3MBTL3-HA and GFP-BRD2-V5 for 48 h and lysates were incubated with 5 μM KL-7 for 2 h, followed by V5 immunoprecipitation (n = 2). D) Excess JQ1 ligand blocks KL-7 induced BRD2 degradation. HCT116 cells were pre-treated 100 μM JQ1 for 1.5 h, and then co-treated with 5 μM KL-7 for 12 h. Quantitation is below and the quantified data represent mean ± SEM (n = 2, **P<0.005). E) KL-7 induced BRD2 degradation is L3MBTL3-dependent. L3MBTL3 wildtype (WT) and Knockout (KO) 293T cells were treated with 5 μM KL-7 for 8 h. Quantitation is below and the quantified data represent mean ± SEM (n = 2, ****P<0.0001). F) KL-7 induced BRD2 degradation is neddylation and proteasome-dependent. HCT116 cells were pre-treated with 1 μM MLN4924 and 0.5 μM epoxomicin for 1.5 h, and then co-treated with 5 μM KL-7 for 12 h. Quantitation is on the right and the quantified data represent mean ± SEM (n = 2, **P<0.005).

Journal: Journal of the American Chemical Society

Article Title: Hijacking Methyl Reader Proteins for Nuclear-Specific Protein Degradation

doi: 10.1021/jacs.2c00874

Figure Lengend Snippet: A) Schematic of BRD and L3MBTL3 proteins in complex with the JQ1-UNC1215 PROTAC. Figure was created with BioRender.com Structure of KL-7. B) KL-7 degrades BRD2 in a dose-dependent manner in HCT116 cells. HCT116 cells were treated with increasing concentrations of KL-7 for 12 h. Quantitation is on the right and the quantified data represent mean ± SEM (n = 3, ****P<0.0001). C) BRD2 forms a ternary complex with L3MBTL3 in a KL-7 dependent manner. HEK293T cells were co-transfected with L3MBTL3-HA and GFP-BRD2-V5 for 48 h and lysates were incubated with 5 μM KL-7 for 2 h, followed by V5 immunoprecipitation (n = 2). D) Excess JQ1 ligand blocks KL-7 induced BRD2 degradation. HCT116 cells were pre-treated 100 μM JQ1 for 1.5 h, and then co-treated with 5 μM KL-7 for 12 h. Quantitation is below and the quantified data represent mean ± SEM (n = 2, **P<0.005). E) KL-7 induced BRD2 degradation is L3MBTL3-dependent. L3MBTL3 wildtype (WT) and Knockout (KO) 293T cells were treated with 5 μM KL-7 for 8 h. Quantitation is below and the quantified data represent mean ± SEM (n = 2, ****P<0.0001). F) KL-7 induced BRD2 degradation is neddylation and proteasome-dependent. HCT116 cells were pre-treated with 1 μM MLN4924 and 0.5 μM epoxomicin for 1.5 h, and then co-treated with 5 μM KL-7 for 12 h. Quantitation is on the right and the quantified data represent mean ± SEM (n = 2, **P<0.005).

Article Snippet: Cell lines HEK293T cells, THP1 and HCT116 cells were purchased from ATCC.

Techniques: Quantitation Assay, Transfection, Incubation, Immunoprecipitation, Knock-Out

Figure 1: )e inhibitory effect of HHTon nine AML cell lines. (a) )e IC50 values of HHTon nine AML cell lines. (b) )e inhibitory effect of HHT on FLT3-ITD mutant cell lines was significantly higher than that in nonmutant ones. ∗P < 0.05.

Journal: Journal of oncology

Article Title: Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance.

doi: 10.1155/2022/2813938

Figure Lengend Snippet: Figure 1: )e inhibitory effect of HHTon nine AML cell lines. (a) )e IC50 values of HHTon nine AML cell lines. (b) )e inhibitory effect of HHT on FLT3-ITD mutant cell lines was significantly higher than that in nonmutant ones. ∗P < 0.05.

Article Snippet: AML cell lines THP-1 (CVCL_0006), HL-60 (CVCL_A794), NB4 (CVCL-0005), Kasumi-1 (CVCL_0589), MOLM-13 (CVCL_2119), MV4-11 (CVCL_0064), KG-1 (CVCL_0374), and U937 (CVCL_0007) were purchased from American Type Culture Collection (ATCC), and OCI-AML3 (CVCL_1844) was purchased from Deutsche Sammlung vonMikroorganismen und Zellkulturen (DSMZ).

Techniques: Mutagenesis

Figure 6: Verification of the hub genes (CALCRL and GNAI1) and the prognostic significance of CALCRL and GNAI1 for AML. (a) )e mRNA level of GPR183, CNR2, CALCRL, and GNAI1 in four AML cell lines by RT-qPCR. (b) )e protein level of CALCRL and GNAI1 in four AML cell lines and the mice tumor mass from HHT-sensitive and HHT-resistant mice groups. (c) )e expression level and OS of GNAI1 and CALCRL in online database GEPIA in AML. (d) )e OS and EFS of CALCRL in our cohorts. (e) )e correlation of GNAI1 and CALCRL through correlation analysis. P < 0.01∗∗and P < 0.001∗∗∗.

Journal: Journal of oncology

Article Title: Characterization of the Newly Established Homoharringtonine- (HHT-) Resistant Cell Lines and Mechanisms of Resistance.

doi: 10.1155/2022/2813938

Figure Lengend Snippet: Figure 6: Verification of the hub genes (CALCRL and GNAI1) and the prognostic significance of CALCRL and GNAI1 for AML. (a) )e mRNA level of GPR183, CNR2, CALCRL, and GNAI1 in four AML cell lines by RT-qPCR. (b) )e protein level of CALCRL and GNAI1 in four AML cell lines and the mice tumor mass from HHT-sensitive and HHT-resistant mice groups. (c) )e expression level and OS of GNAI1 and CALCRL in online database GEPIA in AML. (d) )e OS and EFS of CALCRL in our cohorts. (e) )e correlation of GNAI1 and CALCRL through correlation analysis. P < 0.01∗∗and P < 0.001∗∗∗.

Article Snippet: AML cell lines THP-1 (CVCL_0006), HL-60 (CVCL_A794), NB4 (CVCL-0005), Kasumi-1 (CVCL_0589), MOLM-13 (CVCL_2119), MV4-11 (CVCL_0064), KG-1 (CVCL_0374), and U937 (CVCL_0007) were purchased from American Type Culture Collection (ATCC), and OCI-AML3 (CVCL_1844) was purchased from Deutsche Sammlung vonMikroorganismen und Zellkulturen (DSMZ).

Techniques: Quantitative RT-PCR, Expressing